Magnolia Bark

Magnolia bark extract (95% magnolol and honokiol) shows potent neuroprotective and sedative effects.  Magnolol and honokiol also demonstrate anti-arthritic and anti-cancer effects.  A recent study confirmed that magnolol stimulates cannabinoid receptors which may explain its similar health benefits.

Magnolol shows anti-epileptic effects:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221106/

Magnolol reduces anxiety:
http://pubs.acs.org/doi/abs/10.1021/np9702446

Magnolol reduces pain and inflammation:
https://link.springer.com/article/10.1007%2FBF00168746?LI=true

Magnolol inhibits the development of arthritis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281074/