The benefit of suppositories:
Studies have shown that suppositories provide a 2x absorption efficiency over inhalation and 3x absorption efficiency in comparison to Oral consumption. Vaginal and rectal suppositories are very fast acting, often within 10-15 minutes, with effects often lasting 4-8 hours, however absorption and response varies based on individuals.
Avoiding the gastrointestinal tract prevents first-pass metabolism by the stomach and liver (which metabolize many different molecules into inactive compounds) allowing the active constituents to reach the blood in much higher concentrations. The liver transforms approximately half of THC ingested into the significantly more psychoactive metabolite 11-Hydroxy-Δ9-tetrahydrocannabinol. This molecule causes much more intense cognitive effects than THC. Vaginal and Rectal administration not only avoids these effects, but also allows a much greater proportion of CBD and THC to reach the blood stream.